Acid-Base calculator

Here it is; the new-look acid-base calculator. (20 March 2000)

How to use the program

You can change the values for CO2 and Hydrogen ion concentration by

You can change the units from the choice boxes.
This version of the program allows you to choose which of the 3 variables is dependent, using the check boxes at lower left.

References

The diagram:
    LIG Worthley (1977)  "Hydrogen ion metabolism"  Anaesth.Intens.Care.,5,347-360.
Henderson-Hasselbalch equation:
    Douglas, A.R., N.L.Jones, et al.(1988) "Calculation of whole blood CO2 content" J Appl Physiol 65(1): 473-7.
Base Excess:
    Siggaard-Andersen, O.(1966) "Titratable acid or base of body fluids" Ann N Y Acad Sci 133(1): 41-58.

Note that Base Excess is the in vitro value calculation for whole blood described by Siggaard-Andersen.  To calculate Standard Base excess, also known as in vivo base excess simply set the haemoglobin value to 5 g/100ml.

The equations used can be found in the Java documentation for the "beans" used in this program.
Validation of these equations can be found here.

Comments

Please let me know what you think. david.sainsbury@adelaide.edu.au
Any ideas for enhancements enthusiastically included.

Links

Dr. Lawrence Martin has written an excellent exposition of the principles involved
The display has been updated to show pH and Hydrogen ion concentrations on his recommendation.
See also Nasr Anaizi's intriguing site for a description of the principles.
For a different layout see the interactive diagram by Dr Grogono that plots CO2 against Base Excess

This diagram is the basis of a talk on Java programming you can see by following this link. 

This diagram has been updated in line with  the Javaman project.

Update soon.