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Ovarian and Follicular Function

Ovarian research examines the basic physiology and biology of the ovary to improve clinical outcomes, particularly in polycystic ovary syndrome. Research also investigates the cellular biology of the ovarian follicle. Current research programs are directed at -

• The role of leukocytes and in particular macrophages in the ovary and the way that they interact with the theca, granulosa layers and the oocyte.
• The mechanisms whereby polycystic ovary syndrome is expressed and the contribution of androgen receptor action and polymorphisms.
• The interrelationships between diet, nutrition and ovarian function as evidenced by polycystic ovary syndrome.
• The study of the extracellular matrix, including the follicular basal lamina and the genesis of the epithelial membrana granulosa

In 2004, RCRH research in conjunction with Reproductive Medicine Laboratories produced 'The Egg Timer' test, which measures blood hormone levels in conjunction with a pelvic ultrasound to test for the proportion of good quality eggs left within a woman's ovaries at any given time (ovarian reserve). This test helps women to compare their chronologic and biological age and assist family planning.

Key contacts
Prof Robert Norman
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Professor David Armstrong
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A/Prof Ray Rodgers
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Dr Rob Gilchrist
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Dr Darryl Russell
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Dr Kelton Tremellen
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Dr Rebecca Robker
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