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Michael HorowitzProfessor Michael Horowitz, MBBS, PhD, FRACP

Also check this link to the University Staff Directory as it may contain a more updated profile of this staff member including expertise and contact details.

Current appointments:
Professor (Personal Chair, University of Adelaide) in the Discipline of Medicine, Royal Adelaide Hospital
Director, Endocrine & Metabolic Unit, Royal Adelaide Hospital
Member, Hanson Institute
Adjunct Professor (St Louis University) in the Department of Internal Medicine, St Louis, USA

Staff
Ms Judith Wishart, Research Assistant

Higher Degree students
Dr Marianne Chapman - PhD
Ms Barbara Parker - PhD
Ms Diana Gentilcore - PhD
Ms Amelia Pilchiewicz, Dawes Postgraduate Scholar - PhD
Ms Julie Stevens - PhD
Dr Renuka Visvanathan - PhD
Ms Tanya Little - PhD
Ms Reawika Chaikomin - PhD

Current Funded Research
2002-2004 R Fraser, J Dent, M Horowitz, R Holloway, R Young, K Jones
National Health and Medical Research Council Project Grant Project title: Upper gastrointestinal motor and absorptive function in critically ill patients Value $259,000

2003-2005 C Feinle, M Horowitz, N Talley, K Jones National Health and Medical Research Council Project Grant Project title: The relationships between diet and gastric motor function in functional dyspepsia Value: $210,000

2003-2005 M Horowitz, K Jones, C Feinle, M Samsom, A Smout National Health and Medical Research Council Project Grant Project title: Gastroduodenal motility and glycaemic control in diabetes Value: $375,000

2004-2006 I Chapman, M Horowitz National Health and Medical Research Council Project Grant Project title: The anorexia of ageing : gastrointestinal control of appetite and feeding in the elderly Value: $188,250

2004 M Horowitz, C Feinle-Bisset, C Rayner, K Jones The Rebecca L Cooper Medical Research Foundation Ltd Project title: Evaluation of gastric and small intestinal motility in diabetes mellitus Value: $16,000

2004 R Chen, J Wishart, H Morris, A Need, BEC Nordin, B Chatterton, M Horowitz Royal Adelaide Hospital Research Project Grant Project title: A longitudinal study of bone density, bone-related biochemical variables and body composition in healthy males Value: $15,000

2004 C Feinle-Bisset, J Meyer, T Rades, M Horowitz, H Morris, J Wishart Royal Adelaide Hospital Research Project Grant Project title: Preliminary studies to evaluate the satiating potency of the free fatty acid, lauric acid, in healthy subjects Value: $23,000

2004 M Horowitz, R Young, L Blackshaw, R Margolskee University of Adelaide Faculty of Health Sciences Research Grant Project title: Intestinal glucose sensing mechanisms and their disruption in diabetes Value: $20,000

Most recent publications

Original Papers

Little T, Russo A, Meyer J, Horowitz M, Smyth D, Tsopelas C, Bellon M, Wishart J, Jones K, Feinle-Bisset C. Free fatty acids have more potent effects on gastric emptying, gut hormones and appetite than triacylglyerides. Gastroenterol (accepted for publication)

Chapman M, Fraser R, Bryant L, Vozzo R, Nguyen N, Tam W, Zacharakis B, Davidson G, Butler R, Horowitz M. Gastric emptying and the organisation of antro-duodenal pressures in the critcally ill. Neurogastroenterol Motil (accepted for publication)

Pilichiewicz A, Chaikomin R, Brennan I, Wishart J, Rayner C, Jones K, Smout A, Horowitz M, Feinle-Bisset C,. Load-dependent effects of duodenal glucose on glycemia, gastrointestinal hormones, antopyloroduodenal motility and energy intake in healthy men. Am J Physiol (accepted for publication)

Kuo P, Rayner C, Jones K, Horowitz M. Pathophysiology and management of diabetic gastropathy. Drugs (accepted for publication)

Feltrin K, Little T, Meyer J, Horowitz M, Rades T, Wishart J, Feinle-Bisset C. Effects of lauric acid on antropylorduodenal motility, plasma CCK and PYY, appetite and energy intake are dependant on load, but not concentration, in healthy humans. J Physiol 2007:581;767-77

Chapman I, Parker B, Doran S, Feinle-Bisset C, Wishart J, Lush C, Chen K, Le Certe C, Burns C, McKay R, Rayner C, Horowitz M. Low dose pramlintide reduced food intake and meal duration in healthy, normal weight adults. Obesity 2007:15;1179-86

Sutherland K, Young R, Cooper N, Horowitz M, Blackshaw A. Phentypic characterisation of taste cells of the mouse small intestine. Am J Physiol 2007:292;G1420-8

Need A G, Horowitz M, Morris H, Moore R, Nordin BEC. Seasonal changes in osteoid thickness and mineralisation lag time in ambulant patents. J Bone Min Res 2007:22;757-61

Oemardi M, Horowitz M, Wishart J, Morris H, Need A, O’Loughlin P, Nordin BEC. The effect of menopause on bone mineral density and bone-related biochemical variables in Indonesian women. Clin Endocrinol (accepted for publication)

Chaikomin R, Wu K-L, Doran S, Jones K, Smout A, Renooij W, Holloway R, Meyer J, Horowitz M, Rayner C. Concurrent manometric and impedance recording to evaluate the effects of hyoscine on motility and flow events, glucose absorption and incretin release. Am J Physiol 2007:292;G1099-104

Pilichiewicz A, Horowitz M, Russo A, Maddox A, Jones K, Schoemann M, Holtmann G, Feinle-Bisset C. Effects of Iberogast on proximal gastric volume, antropyloroduodenal motility and gastric emptying in healthy men. Am J Gastroenterol 2007:102;1276-83.

Nguyen NQ, Fraser RJ, Chapman M, Bryant L, Holloway RH, Vozzo R, Wishart J, Feinle-Bisset C, Horowitz M. Feed intolerance in critical illness is associated with increased basal and nutrient-stimulated plasma cholecystokonin concentrations. Crit Care Med 2007:35;82-88

Brennan I, Otto B, Feltrin K, Meyer, JH, Horowitz M, Feinle-Bisset C.  Intravenous CCK-8, but not GLP-1, suppresses ghrelin and stimulates PYY release in healthy men.  Peptides;2007;28;607-11

Phillips L, Rayner CK, Jones KL, Horowitz M.  An update on autonomic neuropathy affecting the gastrointestinal tract.  Curr Diabetes Reports 2006;6:417-23.

Chaikomin R, Rayner CK, Jones KL, Horowitz M.  Upper gastrointestinal function and glycaemic control in diabetes mellitus.  World J Gastroenterol 2006;12:5611-21.

Chaikomin R, Russo A, Rayner C, Feinle-Bisset C, O’Donovan D, Horowitz M, Jones K.  Effects of lipase inhibition on gastric emptying and alcohol absorption in healthy subjects.  Brit J Nutrit 2006;96:883-7.

Gentilcore D, Hausken T, Horowitz M, Jones KL.  Measurements of gastric emptying of low- and high-nutrient liquids using 3D ultrasonography and scintigraphy in healthy subjects.  Neurogastroenertol Motil 2006;18:1062-8.

Yong T, Phillips L, Horowitz M, Giles N.  Severe hypoglycaemic unawareness in a patient with insulinoma.  Int Med J (accepted for publication).

Little T, Doran S, Meyer JH, Smout AJPM, O’Donovan D, Wu K-L, Jones KL, Wishart J, Rayner CK, Horowitz M, Feinle-Bisset C.  The release of GLP-1 and ghrelin, but not GIP and CCK, by glucose is dependent on the length of small intestine exposed.  Am J Physiol 2006;291:E647-55.

Nguyen NQ, Fraser RJ, Chapman M, Bryant L, Holloway RH, Vozzo R, Wishart J, Feinle-Bisset C, Horowitz M.  Feed intolerance in critical illness is associated with increased basal and nutrient-stimulated plasma cholecystokinin concentrations.  Crit Care Med (accepted for publication).

Horowitz M, Jones KL, Rayner CK, Read NW.  ‘Gastric’ hypoglycaemia – an important concept in diabetes management.  Neurogastroenterol Motil 2006;18:405-7.

Jones KL, O’Donovan DG, Hausken T, Russo A, Lei Y, Horowitz M.  Effects of posture on gastric emptying, transpyloric flow and hunger after a glucose drink in healthy humans.  Dig Dis Sci 2006;51:1331-8.

Gentilcore D, Chaikomin R, Jones KL, Russo A, Feinle-Bisset C, Wishart JM, Rayner CK, Horowitz M.  Effects of fat on gastric emptying of, and the glycemic, insulin and incretin responses to, a carbohydrate meal, in type 2 diabetes.  J Clin Endocrinol Metab 2006;91:2062-7.

Little TJ, Pilichiewicz A, Russo A, Phillips L, Jones KL, Nauck MA, Wishart J, Horowitz M, Feinle-Bisset C.  Effects of intravenous GLP-1 on gastric emptying and intragastric distribution in healthy subjects – relationship with postprandial glycemic and insulinemic responses.  J Clin Endocrinol Metab 2006;91:1916-23.

Wu K-L, Chaikomin R, Doran S, Jones KL, Horowitz M, Rayner CK.  Artificially-sweetened, versus regular mixers, increase gastric emptying and alcohol absorption.  Am J Med 2006;119:802-4.

Feinle-Bisset C, Horowitz M.  Dietary factors in functional dyspepsia.  Neurogastroenterol Motil 2006;18:608-18.

Feltrin K, Patterson M, Ghatei M, Bloom S, Meyer J, Horowitz M, Feinle-Bisset C.  Effect of fatty acid chain length on suppression of ghrelin and stimulation of PYY, GLP-2 and PP secretion in healthy men.  Peptides 2006;27:1638-43.

Phillips L, Horowitz M.  Amylin.  Curr Opin Endocrinol Diabetes 2006;13:191-8.

Rayner CK, Horowitz M (invited commentary).  Gastrointestinal motility and glycemic control in diabetes : the chicken and the egg revisited.  J Clin Invest 2006;116:229-302.

Gentilcore D, Jones KL, O’Donovan DG, Horowitz M.  Postprandial hypotension-novel insights into pathophysiology and therapeutic implications.  Curr Vasc Pharmacol 2006;4:161-171.

Pilichiewicz A, Little T, Brennan I, Meyer J, Wishart J, Otto B, Horowitz M, Feinle-Bisset C.  Effects of load, and duration, of duodenal lipid on antropyloroduodenal motility, plasma CCK and PYY, and energy intake in healthy men. Am J Physiol 2006;290:R668-77.

Horowitz M, Nauck M.  To be or not to be – an incretin or enterogastrone?  Gut 2006;55:148-50.

Stevens JE, Russo A, Delaney CA, Collins PJ, Horowitz M, Jones KL.  Acute effects of C-peptide on gastric emptying in longstanding type 1 diabetics.  Clin Autonom Res 2006;16:55-7.

Gentilcore D, Doran S, Meyer JH, Horowitz M, Jones KL.  Effects of intraduodenal glucose concentration on blood pressure and heart rate in healthy older subjects.  Dig Dis Sci 2006;51:652-6.

Visvanathan R, Horowitz M, Chapman I.  The hypotensive response to oral fat is comparable, but slower compared to carbohydrate in healthy older people.  Brit J Nutr 2006;95:340-5.

Rayner C, Horowitz M.  New management approaches for gastroparesis.  Nature Clin Pract Gastroenterol Hepatol 2005;2:454-62.

Kong M-F, Horowitz M.  Diabetic gastroparesis.  Diabet Med 2005;Suppl4:13-18.

Feinle-Bisset C, Patterson M, Ghatei MA, Bloom SR, Horowitz M.  Fat digestion is required for lipid-induced modulation of ghrelin, peptide Y-Y and pancreatic polypeptide secretion.  Am J Physiol 2005;289:E948-53.

Chaikomin R, Doran S, Jones KL, Feinle-Bisset C, O'Donovan D, Rayner CK, Horowitz M.  Initially more rapid small intestinal glucose delivery increases plasma insulin, GIP and GLP-1, but does not improve overall glycemia in healthy subjects.  Am J Physiol 2005;289:E504-7.

Little T, Feltrin K, Horowitz M, Smout A, Rades T, Meyer J, Pilichiewicz A, Wishart J, Feinle-Bisset C.  Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite and energy intake in healthy men.  Am J Physiol 2005;289:R1090-8.

Russo A, Stevens JE, Chen R, Gentilcore D, Burnet R, Horowitz M, Jones KL.  Insulin-induced hypoglycaemia accelerates gastric emptying of solids and liquids in longstanding type 1 diabetes.  J Clin Endocrinol Metab 2005;90:4489-95.

Gentilcore D, Bryant B, Wishart JM, Morris HA, Horowitz M, Jones KL.  Acarbose attenuates the hypotensive response to oral sucrose in the healthy elderly;  associations with slowing of gastric emptying and stimulation of GLP-1 release.  Am J Med 2005;118:1289-95.

Little T, Horowitz M, Feinle-Bisset C.  Role of CCK in appetite control and body weight regulation.  Obesity Reviews 2005;6:297-306.

Chapman M, Fraser R, Vozzo R, Bryant L, Tam W, Nguyen N, Zacharakis B, Butler R, Davidson G, Horowitz M.  Antropyloroduodenal motor responses to gastric and duodenal nutrient in critically ill patients.  Gut 2005;54:1384-90.

Need AG, O’Loughlin PD, Horowitz M, Nordin BEC.  Relationship between fasting serum glucose, age, body mass index and serum 25 hydroxyvitamin D in postmenopausal women.  Clin Endocrinol 2005;62:738-41.

Jones KL, O’Donovan D, Russo A, Meyer JH, Stevens JE, Lei Y, Keogh J, Tonkin A, Horowitz M.  Effects of drink volume and glucose load on gastric emptying and postprandial blood pressure in healthy older subjects.  Am J Physiol 2005;289:G240-8.

Gentilcore D, Visvanathan R, Russo A, Chaikomin R, Stevens JE, Wishart JM, Horowitz M, Jones KL.  The hypotensive and insulin secretory responses to oral glucose in healthy older subjects are mediated by nitric oxide mechanisms.  Am J Physiol 2005;288:G1227-32.

Chapman I, Parker B, Doran S, Feinle-Bisset C, Wishart J, Strobel W, Wang Y, Burns C, Lush C, Weyer C, Horowitz M.  Effect of pramlintide on satiety and food intake in obese subjects and subjects with type 2 diabetes.  Diabetologia 2005;48:838-48.

Parker BA, Doran S, Wishart J, Horowitz M, Chapman I.  Effects of small intestinal and gastric glucose administration on the suppression of plasma ghrelin concentrations in healthy older men and women.  Clin Endocrinol 2005;62:539-46.

Brennan I, Feltrin K, Horowitz M, Smout AJPM, Meyer JH, Wishart J, Feinle-Bisset C.  Evaluation of interactions between CCK and GLP-1 in their effects on energy intake and antropyloroduodenal motility in healthy men.  Am J Physiol 2005;288:R1477-85.

O’Donovan D, Feinle-Bisset C, Chong C, Cameron A, Tonkin A, Wishart J, Horowitz M, Jones KL.  Intraduodenal guar attenuates the fall in blood pressure induced by glucose in healthy older subjects.  J Gerontol A Biol Sci Med Sci 2005;60:940-6.

Visvanathan R, Chen R, Garcia M, Horowitz M, Chapman I.  The effects of drinks made from simple sugars on blood pressure in healthy older persons.  Brit J Nutrit 2005;93:575-9.

O’Donovan D, Hausken T, Lei Y, Russo A, Keogh J, Horowitz M, Jones KL.  Effect of aging on transpyloric flow, gastric emptying and intragastric distribution in healthy humans – impact on glycemia.  Dig Dis Sci 2005;50:671-6.

O’Donovan D, Horowitz M, Russo A, Feinle-Bisset C, Murolo N, Gentilcore D, Wishart JM, Morris HA, Jones KL.  Effects of lipase inhibition on gastric emptying of, and the glycaemic, insulin and cardiovascular responses to, a high fat/carbohydrate meal in Type 2 diabetes.  Diabetologia 2004;47:2208-14.

Horowitz M, Feinle-Bisset C, Jones K, Nauck M.  Orlistat augments postprandial increases in glucagon-like peptide-1 in obese type 2 patients.  Diabetes Care 2004;27:2770.

Smith E, Need AG, Schultz CG, Horowitz M.  Does the response of bone mass to calcum supplements depend on calcium absorption efficiency?  Eur J Endocrinol 2004;151:759-63.

Parker BA, Ludher AK, Loan TK, Horowitz M, Chapman IM.  Relationships of ratings of appetite to food intake in healthy older men and women.  Appetite 2004;43:227-33.

Feltrin K, Little T, Meyer J, Horowitz M, Smout A, Wishart J, Pilichiewicz A, Rades T, Chapman I, Feinle-Bisset C.  Effects of intraduodenal fatty acids on antropyloroduodenal motility and plasma CCK and GLP-1 in humans vary with their chain length.  Am J Physiol 2004;287:R524-33.

Russo A, Stevens J, Giles N, Krause G, O’Donovan D, Horowitz M, Jones KL.  Effect of the motilin agonist KC 11458 on gastric emptying in diabetic gastroparesis.  Aliment Pharmacol Ther 2004;20:333-8.

Nordin BEC, Need AG, Morris HA, O’Loughlin PD, Horowitz M.  The effect of age on calcium absorption in postmenopausal women.  Am J Clin Nutrit 2004;80:998-1002.

Sturm K, Parker B, Wishart J, Feinle-Bisset C, Jones KL, Chapman I, Horowitz M.  Energy intake and appetite are related to antral area in healthy young and older subjects.  Am J Clin Nutrit 2004;80:656-67.

O’Donovan DG, Doran S, Feinle-Bisset C, Jones KL, Meyer JH, Wishart JM, Morris HA, Horowitz M.  Effect of variations in small intestinal glucose delivery on plasma glucose, insulin and incretin hormones in healthy subjects and type 2 diabetes.  J Clin Endocrinol Metab 2004;89:3431-5.

Visvanathan R, Chen R, Garcia M, Horowitz M, Chapman I.  Blood pressure responses in healthy older people to 50 g carbohydrate drinks with differing glycaemic effects.  Brit J Nutrit 2004;92:335-40.

Nordin BEC, Wishart JM, Clifton PM, McArthur R, Scopacasa F, Need AG, Morris HA, O’Loughlin PD, Horowitz M.  A longitudinal study of bone-related biochemical changes at the menopause.  Clin Endocrinol 2004;61:123-30.

Talley NJ, Quan C, Jones MP, Horowitz M.  The association of upper and lower gastrointestinal tract symptoms with body mass index in an Australian cohort.  Neurogastroenterol Motil 2004;16:413-20.

Need AG, O’Loughlin PD, Morris HA, Horowitz M, Nordin BEC.  The effects of age and other variables on serum parathyroid hormone in postmenopausal women attending an osteoporosis center. J Clin Endocrinol Metab 2004;89:1646-9.

Zhang Q, Horowitz M, Rigda R, Rayner C, Worynski A, Holloway RH.  The effect of hyperglycemia on triggering of transient lower esophageal sphincter relaxations.  Am J Physiol 2004;286:G797-803.

Wittert GA, Turnbull H, Hope P, Morley JE, Horowitz M.  Leptin prevents obesity induced by a high fat diet after diet-induced weight loss in the marsupial Sminthopsis crassicaudata.  Am J Physiol 2004;285:R734-9.

Russo A, Botten R, Kong M-F, Chapman JM, Fraser RJL, Horowitz M, Sun W-M.  Effects of acute hyperglycaemia on anorectal motor and sensory function in diabetes mellitus.  Diabet Med 2004;21:176-82.

Feinle C, Vozzo R, Horowitz M, Talley NJ.  Diet, food intake and disturbed physiology in the pathogenesis of functional dyspepsia – a systematic review.  Am J Gastroenterol 2004;99:170-81.

Rayner CK, Schwartz MP, van Dam PS, Renooij W, de Smet M, Horowitz M, Wishart JM, Smout AJPM, Samsom M.  Upper gastrointestinal responses to intraduodenal nutrient in type 1 diabetes mellitus. Eur J Gastroenterol Hepatol 2004;16:183-9.

Scopacasa F, Wishart JM, Horowitz M, Morris HA, Need AG.  Relation between calcium absorption and serum calcitriol in normal men : evidence for age-related intestinal resistance to calcitriol.  Eur J Clin Nutrit 2004;58:264-9.

Parker B, Sturm K, MacIntosh CG, Feinle C, Horowitz M, Chapman IM.  Relationships between food intake and visual analogue scale ratings of appetite to other sensations in healthy older and young subjects.  Eur J Clin Nutr 2004;58:212-8.

Nordin BEC, O’Loughlin PD, Need AG, Horowitz M, Morris HA.  Radiocalcium absorption is reduced in postmenopausal women with vertebral and most types of peripheral fractures.  Osteoporosis Int 2004;15:27-31.

O’Donovan D, Feinle-Bisset C, Jones K, Horowitz M.  Idiopathic and diabetic gastroparesis.  Current Treat Options Gastroenterol 2003;6:299-309.

O’Donovan D, Feinle-Bisset C, Wishart J, Horowitz M.  Lipase inhibiton attenuates the acute effects of oral fat on food intake in healthy subjects. Brit J Nutrit 2003;90:849-52.

Sturm K, MacIntosh CG, Parker BA, Wishart J, Horowitz M, Chapman IM.  Appetite, food intake and plasma concentrations of cholecystokinin, ghrelin and other gastrointestinal hormones in undernourished older women and well-nourished young and older women.  J Clin Endocrinol Metab 2003;88:3747-55.

Pilichiewicz A, O’Donovan D, Feinle C, Lei Y, Wishart JM, Bryant L, Meyer JH, Horowitz M, Jones KJ.  Effects of lipase inhibition on gastric emptying of, and the glycaemic and incretin responses to, an oil/aqueous drink in type 2 diabetes mellitus.  J Clin Endocrinol Metab 2003;88:3829-34.

Gentilcore D, O’Donovan D, Jones KL, Horowitz M.  Nutrition therapy for diabetic gastroparesis.  Current Diabet Reports 2003;3:418-26.

Stanghellini V, Tosetti C, Horowitz M, Salvioli B, Cogliandro R, Cogliandro L, Corinaldesi R.  Predictors of gastroparesis in outpatients with secondary and idiopathic upper gastrointestinal symptoms.  Digest Liver Dis 2003;35:389-96.

Russo A, Stevens J, Wilson T, Wells F, Tonkin A, Horowitz M, Jones KL.  Guar attenuates the fall in postprandial blood pressure and slows gastric emptying of oral glucose in type 2 diabetes.  Dig Dis Sci 2003;48:1221-9.

Quan C, Talley N, Cross S, Jones M, Hammer J, Giles N, Horowitz M.  Development and validation of the diabetes bowel symptom questionnaire.  Aliment Pharmacol Ther 2003;17:1179-87

Feinle C, O’Donovan D, Doran S, Andrews JM, Wishart J, Chapman I, Horowitz M.  Effects of fat digestion on appetite, antropyloroduodenal motility and gut hormones in response to duodenal fat infusion in humans.  Am J Physiol 2003;284:G798-807.

Berry MK, Russo A, Wishart JM, Tonkin A, Horowitz M, Jones KL.  Effect of a solid meal on gastric emptying of, and the glycemic and cardiovascular responses to, liquid glucose in older subjects.  Am J Physiol 2003:284:G655-662.

Boyd KA, O’Donovan DG, Doran S, Wishart J, Chapman IM, Horowitz M, Feinle C.  Effects of a high-fat diet on gut motility, appetite and plasma hormone responses to duodenal lipid in healthy men.  Am J Physiol 2003;284:G188-196.

Visvanathan R, MacIntosh C, Callary M, Penhall R, Horowitz M, Chapman I.  The nutritional status of 250 older Australian recipients of domiciliary care services, and its association with outcomes at 12 months.  J Am Geriatr Soc 2003;51:1007-11.

Hammer J, Howell S, Bytzer P, Horowitz M, Talley NJ.  Symptom clustering in subjects with and without diabetes mellitus : a population-based study of 15,000 Australian adults.  Am J Gastroenterol 2003;98:391-8.

Jesudason D, Need AG, Horowitz M, O’Loughlin PD, Morris HA, Nordin BEC.  Relationship between serum 25-hydroxyvitaminD and bone resorption markers in vitamin D insufficiency.  Bone 2002;31:626-30.

Rayner CK, Schwartz MP, van Dam PS, Renooij W, de Smet M, Horowitz M, Smout AJPM, Samsom M.  Small intestinal glucose absorption and duodenal motility in type 1 diabetes mellitus.  Am J Gastroenterol 2002;97:3123-30.

Jones KL, Russo A, Berry M, Stevens J, Wishart J, Horowitz M.  A longitudinal study of gastric emptying and upper gastrointestinal symptoms in patients with diabetes mellitus.  Am J Med 2002;15:449-55.

Lee A, Patrick P, Wishart J, Horowitz M, Morley JE.  The effect of miglitol on glucagon-like-peptide-1 secretion and appetite sensations in obese type 2 diabetics.  Diabet Obes Metab 2002;4:329-35.

Scopacasa F, Wishart JM, Need AG, Horowitz M, Morris HA, Nordin BEC.  Bone density and bone-related biochemical variables in normal men : a longitudinal study.  J Gerontol Med Sci 2002;57:M385-91.

Vozzo R, Baker B, Wittert G, Wishart JM, Morris H, Horowitz M, Chapman IM.  Glycaemic, hormone and appetite responses to monosaccharide ingestion in patients with type 2 diabetes.  Metabolism 2002;51:949-57.

Chapman IM, MacIntosh CG, Morley JE, Horowitz M.  The anorexia of ageing.  Biogerontology 2002;3:61-71.

Feinle C, Chapman IM, Wishart J, Horowitz M.  Plasma GLP-1 responses to duodenal fat and glucose infusions in healthy and obese men.  Peptides 2002;23:1491-5.

Feinle C, O’Donovan D, Horowitz M.  Carbohydrate and satiety.  Nutrit Rev 2002;60:155-69.

Talley NJ, Howell S, Jones MP, Horowitz M.  Predictors of turnover of gastrointestinal symptoms in diabetes mellitus.  Am J Gastroenterol 2002;97:3187-94.

Bytzer P, Talley NJ, Hammer J, Young LJ, Jones MP, Horowitz M.  GI symptoms in diabetes mellitus are associated with both poor glycaemic control and diabetic complications.  Am J Gastroenterol 2002;97:604-11

O’Donovan, Feinle C, Tonkin A, Horowitz M, Jones KL.  Postprandial hypotension in response to duodenal glucose delivery in healthy older subjects.  J Physiol (Lond) 2002;540:673-9.

Jones KL, Wishart JM, Berry M, Russo A, Xia HH, Talley N, Horowitz M.  Helicobacter pylori infection is not associated with delayed gastric emptying nor upper gastrointestinal symptoms in diabetes mellitus.  Dig Dis Sci 2002;47:704-9.

Su Y-C, Doran S, Wittert G, Chapman IM, Jones KL, Smout AJPM, Horowitz M.  Effects of exogenous corticotropin-releasing factor on antropyloroduodenal motility and appetite in humans.  Am J Gastroenterol 2002;97:49-57.

Horowitz M, Jones KL, Harding PE, Wishart J.  Relationship between the effects of cisapride on gastric emptying and plasma glucose concentration in diabetic gastroparesis.  Digestion 2002;65:41-6.

Scopacasa F, Need AG, Horowitz M, Wishart JM, Morris HA, Nordin BEC.  Effects of dose and timing of calcium supplementation on bone resorption in early postmenopausal women.  Horm Met Res 2002;34:44-7.

Need AG, Kemp A, Giles N, Morris HA, Horowitz M, Nordin BEC.  Relationships between intestinal calcium absorption, serum vitamin D metabolites and smoking in postmenopausal women.  Osteoporosis Int 2002;13:83-88.

Horowitz M, O’Donovan D, Jones KL, Feinle C, Rayner CK, Samsom M.  Gastric emptying in diabetes : clinical significance and treatment.  Diab Med 2002;19:177-194.

Vozzo R, Su Y-C, Fraser R, Wittert GA, Horowitz M, Malbert CH, Chapman IM.  Antropyloroduodenal and feeding responses to pulsatile and non-pulsatile intraduodenal lipid infusion.  Neurogastroenterol Motil 2002;14:25-34.

MacIntosh C, Morley JE, Wishart J, Morris H, Jansen J, Horowitz M, Chapman I.  Effect of exogenous cholecystokinin (CCK-8) on appetite, food intake, blood glucose and plasma insulin, leptin and endogenous CCK in older and young subjects.  J Clin Endocrinol Metab 2001;86:5830-5837.

MacIntosh CG, Sheehan J, Davani N, Morley JE, Horowitz M, Chapman IM.  The effect of aging on opioid modulation of feeding in humans.  J Am Geriatr Soc 2001;49:162-7.

Russell AW, Horowitz M, Ritz M, MacIntosh C, Fraser R, Chapman IM.  The effect of acute hyperglycaemia on appetite and food intake in type 1 diabetes mellitus.  Diabet Med 2001;18:718-25.

Jones KL, Russo A, Stevens JE, Wishart JM, Berry M, Horowitz M.  Predictors of delayed gastric emptying in diabetes mellitus.  Diabetes Care 2001;24:1264-9.

Hveem K, Sun WM, Hebbard GS, Horowitz M, Doran S, Dent J.  Relationship between ultrasonically detected phasic antral contractions and antral pressure.  Am J Physiol 2001;281:G95-101
Bytzer P, Talley NJ, Leemon M, Young LJ, Jones MP, Horowitz M.  Diabetes mellitus is associated with an increased prevalence of gastrointestinal symptoms.  A population-based survey of 15,000 adults.  Arch Int Med 2001;161:1989-96.

Xia H, Talley NJ, Kam E, Young L, Hammer J, Horowitz M.  Helicobacter pylori infection is not associated with diabetes mellitus, nor with upper gastrointestinal symptoms in diabetes mellitus.  Am J Gastroenterol 2001;96:1039-46.

Su Y-C, Vozzo R, Doran S, Leelakusolvong S, Rayner CK, Chapman IM, Jones KL, Horowitz M.  Effects of the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) on antropyloroduodenal motility and appetite in response to intraduodenal lipid infusion in humans.  Scand J Gastroenterol 2001;36:948-54.

Talley NJ, Bytzer P, Hammer J, Young L, Jones M, Horowitz M.  Psychological distress is linked to gastrointestinal symptoms in diabetes mellitus.  Am J Gastroenterol 2001;96:1033-8.

Rayner C, Samsom M, Jones KL, Horowitz M.  Relationships of upper gastrointestinal motor and sensory function with glycemic control (review).  Diabetes Care 2001;24:371-81.

MacIntosh C, Horowitz M, Verhagen M, Smout A, Wishart J, Morris H, Goble E, Morley JE, Chapman JM.  Effect of small intestinal nutrient infusion on appetite, gastrointestinal hormone release and gastric myoelectrical activity in young and older men.  Am J Gastroenterol 2001;96:997-1007.

Beckoff K, MacIntosh CG, Chapman IM, Wishart JM, Morris HA, Horowitz M, Jones KL.  Effects of glucose supplementation on gastric emptying, blood glucose homeostasis and appetite in the elderly.  Am J Physiol 2001;280:R570-R576.homeostasis and appetite in the elderly.  Am J Physiol 2001;280:R570-R576.

Andrews JM, Doran SM, Hebbard GS, Malbert CH, Horowitz M, Dent J.  Nutrient-induced patterning of human duodenal motor function.  Am J Physiol 2001;280:G501-9.

Jones KL, MacIntosh C, Su Y-C, Wells F, Chapman IM, Tonkin A, Horowitz M.  Guar gum reduces postprandial hypotension older people.  J Am Geriatr Soc 2001;49:162-7.

Bytzer P, Talley NJ, Jones MP, Horowitz M.  Oral hypoglycaemic drugs and gastrointestinal symptoms in diabetes mellitus.  Aliment Pharmacol Ther 2001;15:137-142.

Talley NJ, Young L, Bytzer P, Hammer J, Leemon M, Jones M, Horowitz M.  Impact of chronic gastrointestinal symptoms in diabetes mellitus on health-related quality of life.  Am J Gastroenterol 2001;96:71-6.

Horowitz M, Su Y-C, Rayner CK, Jones KL.  Gastroparesis : prevalence, clinical significance and treatment.  Canad J Gastroenterol 2001;15:805-13.

Scopacasa F, Need AG, Horowitz M, Wishart JM, Morris HA, Nordin BEC.  Inhibition of bone resorption by divided-dose calcium supplementation in early postmenopausal women.  Calcif Tissue Int 2000;67:440-2.

Su Y-C, Wang W-M, Wang S-Y, Lu S-N, Chen C-T, Wu D-C, Chen C-Y, Jan C-M, Horowitz M.  The association between Helicobacter pylori infection and functional dyspepsia in patients with irritable bowel syndrome.  Am J Gastroenterol 2000;95:1900-5.

Scopacasa F, Horowitz M, Wishart JM, Morris HA, Chatterton BE, Need AG.  The relation between bone density, free androgen index and estradiol in men 60 to 70 years old.  Bone 2000;27:145-9.

Anvari M, Myers J, Malbert C, Horowitz M, Jamieson G.  Antral compensation after proximal gastric vagotomy.  J Gastroint Surg 2000;41:526-30.

Rayner CK, Su Y-C, Doran SM, Jones KL, Malbert CH, Horowitz M.  The stimulation of antral motility by erythromycin is attenuated by hyperglycemia.  Am J Gastroenterol 2000;95:2233-41.

Rayner CK, MacIntosh CG, Chapman IM, Morley JE, Horowitz M.  Effects of age on proximal gastric motor and sensory function.  Scand J Gastroenterol 2000;35:1041-7.

Jones KL, Wishart JM, Berry MK, Abitbol J-L, Horowitz M.  Effects of fedotozine on gastric emptying and upper gastrointestinal symptoms in diabetic gastroparesis.  Aliment Pharmacol Ther 2000;14:937-43.

Wishart JM, Scopacasa F, Horowitz M, Morris HA, Need AG, Clifton PM, Nordin BEC.  Effect of perimenopause on calcium absorption : a longitudinal study.  Climateric 2000;3:102-108.

Need AG, Horowitz M, Morris HA, Nordin BEC.  Vitamin D status : effects on parathyroid hormone and 1,25 dihydroxyvitamin D in postmenopausal women.  Am J Clin Nutrit 2000;71:1577-81.

Rayner CK, Verhagen MAMT, Hebbard GS, DiMatteo AC, Doran SM, Horowitz M.  Proximal gastric compliance and perception in type 1 diabetes mellitus – effects of hyperglycemia.  Am J Gastroenterol 2000;95:1175-83.

Hope PJ, Turnbull H, Breed W, Morley JE, Horowitz M, Wittert GA.  The effect of ovarian steroids and photoperiod on body fat stores and uncoupling protein 2 in the marsupial Sminthopsis crassicaudata. Physiol Behav 2000;69:463-70.

Sun WM, Doran SM, Jones KL, Davidson G, Dent J, Horowitz M.  Long-term effects of pyloromyotomy on pyloric motility and gastric emptying in humans.  Am J Gastroenterol 2000;95:92-100.

Rayner CK, Park HS, Doran SM, Chapman IM, Horowitz M.  Effects of cholecystokinin on appetite and pyloric motility during physiological hyperglycemia.  Am J Physiol 2000;278:G98-104.

Rayner CK, Park HS, Wishart JM, Kong M-F, Doran S, Horowitz M.  Effects of intraduodenal glucose and fructose on antropyloric motility and appetite in healthy humans.  Am J Physiol 2000;278:R360-366.

Books

Horowitz M, Samsom M (Editors).  Gastrointestinal function in diabetes mellitus.  John Wiley and Sons, 2004.

 

Book Chapters

Kong M-F, Horowitz M.  Diabetes.  In:  Fecal Incontinence:  Diagnosis and Treatment.  Editors, Ratto, C, Doglietto GB.  Springer Verlag 2007

Rayner C, Horowitz M.  Changes in gastrointestinal motor and sensory function associated with aging.  In:  Principles and Practice of Geriatric Medicine, 4th edition.  Editors, Pathy MSJ, Sinclair A and Morley JE.  John Wiley and Sons, 2006, pp 357-369.

Rayner C, Horowitz M.  Aging and the gastrointestinal tract.  In:  Merck Manual of Geriatrics (4th edition).  Editors, MH Beers, R Berkow.  Merck Research Laboratories 2005, p 1000-1005.

O’Donovan D, Jones K, Feinle C, Horowitz M.  Gastric emptying.  In: Encyclopedia of Gastroenterology.  Editor:  Johnson LR.  Academic Press, 2004;118-24.

Feinle C, O’Donovan D, Horowitz M.  Gastric motility.  In:  Encyclopedia of Gastroenterology.  Editor:  Johnson LR.  Academic Press, 2004;132-8.

O’Donovan D, Feinle C, Jones K, Horowitz M.  Gastrointestinal disorders in diabetes.  In:  Textbook of Diabetes, 3rd edition.  Editors Pickup J, Williams G, Blackwell Science 2002;59.1-59.16.

O’Donovan, Samsom M, Feinle C, Jones KL, Horowitz M.  Gastrointestinal tract.  In:  Textbook of Diabetic Neuropathy.  Editors: F Gries, N Cameron, P Low, D Ziegler.  Thieme Verlag, Stuttgart/New York 2002;246-62.

Horowitz M.  Aging and the gastrointestinal tract.  In : Merck Manual of Geriatrics (third edition).  Editors:  M.H. Beers, R Berkow, 2000:1000-1006.

Nordin BEC, Need AG, Morris HA, Horowitz M. Bone disease and ageing.  In:  Endocrinology and Aging.  Editors:  JE Morley, L van den Berg,  Humana Press, Totowa NJ, 2000;93-108.