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 Dr
Mounir N Ghabriel
MBBCh (University of Assiut, Assuit, Egypt)
PhD (University of London,UK)
Associate Professor of Anatomy
E-mail: mounir.ghabriel@adelaide.edu.au
Teaching
Mounir has a strong interest in teaching with over twenty-years experience
in teaching human anatomy to undergraduate and postgraduate students.
He taught anatomy at universities in Europe, Australia, Africa and America.
Current teaching responsibilities to undergraduate and postgraduate students
include: lectures, practical demonstrations in the dissecting laboratory,
small group tutorials and case-based teaching / clinical correlation in
gross anatomy, neuroanatomy and embryology to medical, dental, physiotherapy,
occupational therapy, health science and science students.
Research Interests
Mounir is the head of the Blood-Brain
Barrier Group. He is interested in the structure and function of the
central and peripheral nervous systems in normal and pathological conditions
such as demyelination, degeneration and trauma. A focus of the group's
research is the study of permeability barriers in brain and spinal cord
trauma. The methodology includes the use of light and electron microscopy,
freeze-fracture, immunocytochemistry, application of tracers and western-blotting.
The Blood-Brain Barrier Group consists of :
Dr Mounir Ghabriel
Dr Rami Tadros
Dr Jianjun Lu
Mrs Gail Hermanis
Mr Chris Leigh
Ms Irena Zdziarski
Mrs Heidi Magar
Miss Amber Thomas
Mr YuChao Lee
Miss Dawn Lee
Mr Abdul Imran
Collaborators
Mounir has current collaborative projects with:
Within the discipline
Professor Brian Setchell, Reproductive Biology
Group
Dr Bruce Firth, Circadian Rhythm Group
External:
Professor Peter Blumbergs and Associate Professor Robert Vink, Neurotrauma group,
The Institute of Medical and Veterinary Science, Adelaide.
Professor Nigel Jones and Professor Peter Reilly, Department Neurosurgery, The
University of Adelaide ( Medical School)
Dr Chunni Zhu, Department of Medicine, School of Medicine, UCLA, CA, USA.
Recent Publications
- Ghabriel M N, Zhu C, Hermanis G, Allt G (2000) Immunological targeting
of the endothelial barrier antigen (EBA) in vivo leads to opening of the blood-brain
barrier. Brain Research, 878: 127-135.
- Ghabriel MN, Zhu C, Reilly PL, Blumbergs PC, Manavis J and Finnie JW
(2000) Toxin-induced Vasogenic cerebral oedema in a rat model. Acta Neurochirorgica,
[Suppl] 76, 231-236.
- Zhu C, Ghabriel MN, Blumbergs PC, Reilly PL, Manavis J, Youssef J, Hatami
S, Finnie JW (2001) Clostridium perfringens prototoxin-induced alteration
of endothelial barrier antigen (EBA) immunoreactivity at the blood-brain barrier
(BBB). Experimental Neurology,169: 72-82.
- Ghabriel MN, Lu JJ, Hermanis G, Zhu C and Setchell BP (2002) Expression
of a blood-brain barrier-specific antigen in the rat male reproductive tract.
Reproduction , 123, 389-397
- Ghabriel MN, Zhu C, Leigh C (2002) Electron microscope study of blood-brain
barrier opening induced by immunological targeting of the endothelial barrier
antigen. Brain Research , 934: 140-151.
- Ghabriel M N, Lu J, Tadros R and Hermanis G (2004) A narrow time-window
for access to the brain by exogenous protein after immunological targeting
of a blood-brain barrier antigen. Journal of Comparative Pathology, 131: 52-60.
- Peppi M and Ghabriel M N (2004) Tissue-specific expression of the
tight junction proteins claudins and occludin in the rat salivary glands.
Journal of Anatomy, 205: 257-266
- Ghabriel M, Zhu C, Imran A, Blumbergs P and Reilly P (2004) Blood-brain
barrier ultrastructural changes in impact acceleration head trauma. Proceedings
of the 7th international Neurotrauma Symposium, Adelaide, Australia, pp 89-92.
- Bhatia K, Ghabriel MN, Henneberg M (2005) Anatomical variations in
the branches of the human aortic arch: a recent study of a South Australian
population. Folia Morphologica, 64: 217-223
- Ghabriel MN, Thomas A, Vink R (2006) Magnesium restores altered aquaporin-4
immunoreactivity following traumatic brain injury to a preinjury state. Acta
Neurochirurgica Suppl, 96: 402-406
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