|
|
 Professor
Emeritus Brian Setchell
BVSc (Sydney University)
PhD ScD (University of Cambridge)
Prof. Brian Setchell has a long-standing interest in the physiology, biochemistry,
and endocrinology of the testes and epididymis with particular reference
to the blood-testis barrier, testicular fluids and blood flow, the descent
of the testis, cryptorchidism and the effects of whole body or local heating
of the testes on sperm production, motility, fertilising ability, and the
development of embryos in normal females made pregnant by males whose testes
had been heated.
Until the end of 1996, he was Professor of Animal Sciences in the Faculty
of Agricultural and Natural Resource Sciences at the Waite Campus and
spent 1997-8 as a Nobel Foundation Fellow and 2000 as a STINT fellow at
the Pediatric Endocrinology Unit, Karolinska Hospital, Stockholm, Sweden.
He has published a book "The Mammalian Testis", and 69 major
reviews and chapters in books, 136 original research articles, and 203
abstracts on the work of his group on the testis and epididymis, as well
as translations of de Graaf's two books on Male and Female Reproductive
Organs (originally published in 1668 and 1672 respectively) as well as
of Sertoli's original 1865 article describing the cells in the testes
named after him. He was given the Distinguished Andrologist award for
1997 by the American Society of Andrology.
Recent Publications
- JC Bustamante, BP Setchell (2000) The permeability of the microvasculature
of the perfused rat testis to small hydrophilic substances. Journal
of Andrology 21: 444-451
- JC Bustamante, BP Setchell (2000) The uptake of amino
acids, in particular leucine, by isolated perfused testes of rats. Journal
of Andrology 21: 452-463
- BP Setchell , L Ploen and EM Ritzen (2001) Reaction of long-term
effects of local heating of the testis by treatment of rats with a GnRH
agonist and an anti-androgen. Reproduction 122, 255-263.
- K Jahnukainen ,M Hou ,C Petersen ,BP Setchell and O Soder (2001)
Intratesticular transplantation of testicular cells from leukemic rats
causes transmission of leukemia. Cancer Research 61, 706-710.
- CK Jonsson , BP Setchell , N Martimeller , K Svechnikor and O Soden
(2001) Endotoxin-induced expression in testicular macrophages is
accompanied by downregulation of the constitutive expression in Sertoli
cells. Cytokine 14, 283-288
- BP Setchell (2001) Physiologie de la barriere sang-testicule.
Andrologie 11, 15-20
- BP Setchell (2002) Innervation and vasculature of the excurrent
duct system. In; The Epididymis. ed B.Robaire and BT hinton, New York
, Kluwer Academic/Plenum Publishers, pp 35-48
- Ghabriel MN, Lu JJ, Hermanis G, Zhu C and Setchell BP (2002)
Expression of a blood-brain barrier-specific antigen in the rat male
reproductive tract. Reproduction , 123, 389-397
- BP Setchell, L Plöen and EM Ritzen (2002) Effect of local
heating of rat testes after suppresion of spermatogenesis by pretreatment
with a GnRH agonist and an antiandrogen. Reproduction, 124.133-140 .
- Setchell BP, Pakarinen P and Huhtaniemi I (2002) How much LH
do the Leydig cell see? Journal of Endocrinology 175, 375-382.
- Gustafsson K, Sultana T, Zetterstrom CK, Setchell BP, Siddiqui
A, Weber G and Soder O (2002) Production and secretion of interleukin-1ý
proteins byrat testis. Biochemical and Biophysical Research Communications.
297, 492-497
- Setchell BP, Hertel T, Soder O. (2003) Postnatal testicular
development, cellular organization and paracrine regulation. In: The
Developing Testis
Physiology and Patholophysiology, ed O. Soder. Basel, Karger. pp 24-37.
- Setchell, BP (2004) Hormones: what the testis really sees.
Reproduction, Fertility and Development, (in press)
Other Publications of Interest
- BP Setchell (1978) "The Mammalian Testis" Elek Books,
London Cornell University Press, Ithaca. 450pp
- BP Setchell (1984) " Male Reproduction. Benchmark papers
in Human Physiology Volume 17. Van Nostrand Reinhold Comapny, New York
401pp
>
Staff
|
